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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: J Pain Symptom Manage. 2019 Jul 2;58(4):605–613. doi: 10.1016/j.jpainsymman.2019.06.024

Figure 2. Change in Dyspnea Intensity and Walk Distance With and Without Study Medications.

Figure 2.

(A) In the high dose fentanyl sublingual spray (FSS) group, significantly lower modified dyspnea Borg scale (mean change −1.4; 95% CI −2.4, −0.5; P=0.007) was observed between the first (no medication) and second (10 minutes after FSS administration) walk. (B) In the low dose FSS group, there was also a non-significant reduction in modified dyspnea Borg scale (mean change −0.5; 95% CI −1.3, 0.3; P=0.24). Walk distance was increased after both high ([C]; mean change 44 m; P=0.001) and low ([D]; mean change 24 m; P=0.01) dose FSS administration as compared to baseline.