Table 2.
FEP (anti-NMDAR Ab) |
HC (anti-NMDAR Ab) |
|||||
---|---|---|---|---|---|---|
Dependent | β | t | p | β | T | p |
MCCB | ||||||
Speed of Processing | −0.79 | −2.37 | 0.02* | −0.04 | −0.15 | 0.88 |
Working Memory | −1.16 | −4.23 | 6.01 ×10−5* | −0.45 | −1.46 | 0.15 |
Verbal Learning | −1.24 | −3.92 | 1.78×10−4* | 0.07 | 0.22 | 0.83 |
Attention and Vigilance | −0.71 | −1.83 | 0.07 | −1.81 | −3.19 | 0.95 |
Visual Learning | −0.66 | −2.01 | 0.05 | −0.09 | −0.36 | 0.72 |
R/Problem Solving | −0.30 | −0.86 | 0.39 | −0.09 | −0.08 | 0.94 |
Social Cognition | −0.35 | −0.94 | 0.35 | 0.02 | 0.05 | 0.96 |
Total score | −0.96 | −3.65 | 4.63×10−4* | −0.22 | −0.79 | 0.44 |
PANSS | ||||||
Positive score | 0.38 | 2.55 | 0.01* | NA | NA | NA |
Negative score | 0.53 | 2.94 | 4.24 ×10−3* | NA | NA | NA |
General score | 0.13 | 0.63 | 0.53 | NA | NA | NA |
Total score | 1.01 | 2.81 | 6.13 ×10−3* | NA | NA | NA |
Abbreviations: FEP, First Episode Patients with Schizophrenia; HC, Healthy Controls;MCCB, MATRICS Consensus Cognitive Battery; NA, not applicable; PANSS, Positive and Negative Syndrome Scale. General linear regression was used. The source was NMDAR antibody level (ng/ml), the dependents were subscores and total score of MCCB and PANSS, the covariate was age, sex and education, data on the final models were presented.
Significant at p<0.05