Figure 3.

Knockdown of DKK2 promoted tumor cells' migration ability. (a) The enrichment plots in DKK2-highly expressed group compared to the low performed by gene set enrichment analysis. (b) Transwell assay showed that silencing DKK2 led to more migrated cells in AsPC-1 and CAPAN-1. For each transwell assay, the cell number was counted (c). (d) Movement of DKK2 knockout and control cells into the wound was shown in AsPC-1 and CAPAN-1 at 0 h and 12 h. The percentage of wound healing was assessed (e). Significant differences are indicated as ^∗P < 0.05 and ^∗∗P < 0.001.