Table 4.
Binomial logistic regression analysis of the CFI rs10033900, ERCC6 rs3793784, VEGFA rs833068, HTRA1 rs11200638, TIMP3 rs9621532, and KCTD10 rs56209061 SNPs in early AMD and control groups.
| Early AMD | |||
|---|---|---|---|
| SNP | Model/genotype/allele | OR; 95% CI; P∗ | AIC |
| Codominant | |||
| rs56209061 | GA vs. GG | 0.471; 0.307-0.724; 0.001 | 842.895 |
| AA vs. GG | 0.343; 0.066-1.786; 0.204 | ||
|
| |||
| Dominant | |||
| rs56209061 | GA+AA vs. GG | 0.463; 0.305-0.704; <0.001 | 841.036 |
|
| |||
| Recessive | |||
| rs3793784 | CC vs. GC+GG | 2.007; 1.255-3.209; 0.004 | 845.769 |
|
| |||
| Overdominant | |||
| rs56209061 | GA vs. GG+AA | 0.478; 0.312-0.733; 0.001 | 842.698 |
|
| |||
| Additive | |||
| rs11200638 | A | 1.387; 1.096-1.755; 0.007 | 847.056 |
| rs56209061 | A | 0.491; 0.332-0.726; <0.001 | 841.104 |
OR: odds ratio; 95% CI: 95% confidence interval; P values < 0.008 indicated in bold are statistically significant; AIC: Akaike information criterion.