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. 2019 Sep 8;2019:1845321. doi: 10.1155/2019/1845321

Figure 4.

Figure 4

Mitochondrial Ca2+ uptake measurements in skATG7−/− mice. (a) Resting mitochondrial [Ca2+] was decreased in skATG7−/− FDB myofibers compared to ATG7fl/fl controls. Data are presented as mean ± SD (>10 fibers per condition). (b) Ratiometric measurements of mitochondrial Ca2+ uptake upon caffeine treatment highlighted a reduction in peak mitochondrial [Ca2+] of skATG7−/− FDB myofibers compared to ATG7fl/fl controls. p < 0.05, t test (two-tailed, unpaired) of >10 fibers per condition. Data are presented as mean ± SD. (c) Representative traces of mitochondrial Ca2+ uptake measurements.