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. 2019 Sep 8;2019:2165918. doi: 10.1155/2019/2165918

Figure 2.

Figure 2

Inhibition of synovial macrophage pyroptosis may alleviate synovitis in KOA rats. (a) Representative synovial tissues of each group stained with HE staining (200×). Arrow: inflammatory cell infiltration. (b) Protein expressions of IL-1β, IL-18, and HMGB1 between groups. ∗P < 0.05, in comparison with the Normal group. #P < 0.05, in comparison with the KOA group (n = 6). (c) Typical protein bands for each group. (d) mRNA levels of IL-1β, IL-18, and HMGB1 between groups. The trend is consistent with protein expression.