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. 2019 Sep 8;2019:2165918. doi: 10.1155/2019/2165918

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Copyright © 2019 Li Zhang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Macrophage pyroptosis upregulates the expression of fibrosis markers cocultured with synovial fibroblasts. (a) Comparison of TGF-β, PLOD2, COL1A1, and TIMP1 protein expressions between groups. ^∗P < 0.05, in comparison with the Normal group. ^#P < 0.05, in comparison with the KOA group. (b) Typical protein bands for each group. (c) Relative mRNA expression of TGF-β, COL1A1, PLOD2, and TIMP1 in synovial fibroblasts in each group. ^∗P < 0.05, in comparison with the Normal group. ^#P < 0.05, in comparison with the KOA group.