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. 2019 Sep 8;2019:2782417. doi: 10.1155/2019/2782417

Figure 5.

Figure 5

Effect of premicroinjection and postmicroinjection of MZF1 siRNA on CCI-induced neuropathic pain. (a, b) Premicroinjection of MZF1 in the ipsilateral DRG prevented the CCI-induced decrease in PWT (a) and PWL (b). ∗P < 0.05 and ∗∗P < 0.01 vs. the vehicle+CCI group (two-way ANOVA). (c, d) Postmicroinjection of MZF1 in the ipsilateral DRG abolished the established CCI-induced nociceptive changes in PWT (c) and PWL (d). ∗∗P < 0.01 vs. the CCI+vehicle group (two-way ANOVA). No change was observed in PWT and PWL of rats premicroinjected or postmicroinjected with MZF1 scrRNA (a–d).