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. 2019 Sep 19;7:e7695. doi: 10.7717/peerj.7695

Table 4. Published levels of vitamin K in serum.

References Region Phylloquinone (ng/mL) Menaquinone-4 (ng/mL) Menaquinone-7 (ng/mL)
Tsugawa et al. (2006) Japan Premenopausal women 30–49 years (n = 52)
Postmenopausal women 50–69 years (n = 208)
Postmenopausal women ≥70 years (n = 136)
1.52 ± 1.02
1.74 ± 1.29
1.29 ± 1.09
0.07 ± 0.14
0.10 ± 0.19
0.09 ± 0.15
4.96 ± 6.93
8.42 ± 11.44
4.21 ± 6.81
Riphagen et al. (2016) Netherlands Patients after kidney transplant (n = 60) 0.61 ± 0.21 0.09 ± 0.01 <LoD (2.86)
Klapkova et al. (2018) Czech Republic Postmenopausal women with osteoporosis (n = 192)
Postmenopausal women without osteoporosis (n = 158)
0.43 ± 0.39
0.49 ± 0.40
0.89 ± 0.29
0.83 ± 0.27
1.00 ± 1.02
1.19 ± 1.08
Suttie (1992) UK Young population (n = 11)
Older population (n = 17)
0.51 ± 0.37
0.60 ± 0.28
not measured 0.29 ± 0.18
0.33 ± 0.17
Yan et al. (2004) China Older men (n = 86)
Older women (n = 92)
0.85 ± 0.99
1.12 ± 1.45
not measured not measured
Booth et al. (2004) USA Older men (n = 741) 0.69 ± 0.90 not measured not measured
Kamao et al. (2005) Japan Healthy population (n = 20)
Patients with osteoporosis (n = 10)
1.81 ± 1.11
0.62 ± 0.25
0.15 ± 0.17
46.83 ± 46.41
16.27 ± 20.58
4.18 ± 6.28
Suhara et al. (2005) Japan Healthy population (n = 20) 1.22 ± 0.57 0.39 ± 0.46 6.37 ± 7.45