Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Aug 20;47(17):9216–9230. doi: 10.1093/nar/gkz712

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 2. — Most 3′ fragments of cleaved miRNA targets overaccumulate in xrn4 as polyadenylated RNA. (A) Decay plots (D-plots) of a validated miRNA target transcript ARF10 that overaccumulates 3′ fragment of miR160-guided cleavage in xrn4–5. Black arrow, miRNA-guided cleavage site. (B) The heat map of miRNA targets shows fold changes of 3′ fragment abundance in xrn4 in polyA+ and polyA- PARE (Supplementary Table S3). Abundance at cleavage site (±1 nt) in both xrn4 mutants ≥ 10 TP20M and ≥1.5-fold change.