Table 2.
Lung cancer and mortality at 10 years by randomization arm.
| Total (N=2,376) |
Annual (N=1,190) |
Biennial (N=1,186) |
P-values | |
|---|---|---|---|---|
| Lung cancer incidence | 98 (4.1%) | 58 (4.9%) | 40 (3.4%) | 0.0658 |
| Stage I | 49 (50.0%) | 31 (53.4%) | 18 (45%) | 0.4110 |
| Resected cancers | 64 (65.3%) | 43 (74.1%) | 21 (52.5%) | 0.0004 |
| Adenocarcinoma | 55 (56.1%) | 33 (56.9%) | 22 (55.0%) | 0.8525 |
| Interval cancers | 27 (27.6%) | 14 (24.1%) | 13 (32.5%) | 0.3625 |
| Lung cancers beyond 5 years | 39 (39.8%) | 23 (39.7%) | 16 (40.0%) | 0.9727 |
| Total deaths a | 137 (5.8%) | 76 | 61 | 0.1936 |
| Overall mortality rate (per 100,000) | 593.5 | 659.7 | 527.6 | |
| Lung cancer deaths | 40 (1.7%) | 19 | 21 | 0.7417 |
| Lung cancer mortality rate (per 100,000) | 173.3 | 164.9 | 181.6 | |
| Other causes of deaths | 94 | 56 | 38 | 0.0604 |
| Other causes mortality rate (per 100,000) | 407.2 | 486.1 | 328.7 | |
| Number of LDCTs performed | 12,375 | 7,369 | 5,006 | |
| Number of LDCTs performed after baseline | 10,072 | 6,217 | 3,855 | |
| Number of PETs performed | 51 | 37 | 14 | |
| Benign lung resection | 3 | 0 | 3 |
a
3 missing causes of death (1 Annual arm and 2 Biennial arm).