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. 2019 Aug 22;20(4):3499–3508. doi: 10.3892/mmr.2019.10602

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Copyright: © Dai et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — MALAT1 is increased in prostate cancer cells and inhibits miR-1-3p expression. The relative expression levels of (A) MALAT1 and (B) miR-1-3p in human normal prostatic epithelial cell line, RWPE2, and prostate cancer cell lines PC-3, DU145, LNCaP and 22RV1 were detected by quantitative polymerase chain reaction. The relative levels of (C) MALAT1 and (D) miR-1-3p in prostate cancer cells following MALAT1 knockdown. (E) Western blotting and (F) quantitative analysis of the protein level of CORO1C in MALAT1-silenced prostate cancer cells was detected with GAPDH as the internal control. ***P<0.001. MALAT1, metastasis-associated lung adenocarcinoma transcript 1; CORO1C, coronin 1C; miR, microRNA; NC, negative control; sh, short hairpin.