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. 2019 Aug 29;20(4):3679–3690. doi: 10.3892/mmr.2019.10627

Table II.

Optimal genes list based on Cox proportional hazards model of L1-penalized regularization regression algorithm.

Gene Coef Hazard ratio P-value
ANKS1B −0.605 0.767 (0.658–0.895) 6.568×10−4
CAMK1 −0.179 0.837 (0.729–0.959) 1.045×10−2
CES1 −0.496 0.846 (0.751–0.953) 5.423×10−3
CTLA4 −1.468 0.716 (0.627–0.817) 5.008×10−7
CXCL2 0.948 1.559 (1.219–1.994) 5.637×10−4
DNAJC12 0.379 1.480 (1.239–1.767) 1.332×10−5
EFNA5 −0.619 0.811 (0.719–0.915) 5.862×10−4
FEZ1 0.317 1.214 (1.059–1.390) 5.066×10−3
HOPX −0.114 0.859 (0.750–0.984) 2.703×10−2
HPCAL4 −0.039 0.666 (0.531–0.837) 4.057×10−4
IL17RB 0.187 1.137 (1.023–1.263) 1.627×10−2
MUC16 −0.348 0.837 (0.731–0.957) 8.829×10−3

Coef, coefficient; ANKS1B, ankyrin repeat and sterile α motif domain-containing protein 1B; CAMK1, calcium/calmodulin dependent protein kinase I; CES, carboxylesterase 1; CTLA4, cytotoxic T-lymphocyte associated protein 4; CXCL2, C-X-C motif chemokine ligand 2; DNAJC12, DnaJ heat shock protein family member C12; EFNA5, ephrin A5; FEZ1, fasciculation and elongation protein ζ1; HOPX, HOP homeobox; HPCAL4, hippocalcin like 4; IL17RB, interleukin 17 receptor B; MUC16, mucin 16, cell surface associated.