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. 2019 Sep 2;20(4):3565–3572. doi: 10.3892/mmr.2019.10631

Figure 1.

Figure 1.

Upregulation of IL-6, TNF-α, CRP, TLR4 and TLR5, and downregulation of IL-10 and TLR3 in patients with AS. Serum contents of (A) IL-6, (B) IL-10, (C) TNF-α and (D) CRP in patients with AS and healthy subjects as determined by ELISA. (E) mRNA levels of TLRs as determined via reverse transcription-quantitative PCR analysis. *P<0.05, **P<0.01 vs. control. AS, ankylosing spondylitis; CRP, C-reactive protein; IL, interleukin; TLR, Toll-like receptor; TNF-α, tumor necrosis factor-α.