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. 2019 Aug 9;20(4):3003–3010. doi: 10.3892/mmr.2019.10577

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Copyright: © Zhong et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Downregulation of SREBP2 inhibits ESCC cell growth and migration. (A) Knockdown of SREBP2 expression in ESCC cells. (B) Effects of SREBP2 knockdown on ESCC cell migration were evaluated using Boyden chamber assays. Magnification, ×20. (C) Effects of SREBP2 knockdown on the anchorage-independent growth of ESCC cells were evaluated by soft agar assays. Magnification, ×20. **P<0.01 vs. respective sh con. Con, control; sh, short hairpin RNA; SREBP2, sterol regulatory element-binding protein 2; ESCC, esophageal squamous cell carcinoma.