Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jul 31;20(4):3085–3094. doi: 10.3892/mmr.2019.10541

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 4. — Rapamycin reduces sevoflurane-induced inflammatory response and inhibits the expression of the TLR4/MyD88/NF-κB signaling pathway induced by sevoflurane in aged rats. (A) ELISA was performed to determine the expression levels of IL-1β, IL-6, TNF-α and IL-10. (B) Western blot assays were performed to determine the protein expression levels of apoptosis-related proteins and TLR4/MyD88/NF-κB signaling pathway-related proteins. (C) RT-qPCR was performed to determine the expression levels of TLR4, MyD88 and NF-κB mRNA. *P<0.05 vs. the control group; ^#P<0.05 vs. the SEV group. TLR4, toll-like receptor 4; MyD88, myeloid differentiation primary response 88; NF-κB, nuclear factor-κB; RT-qPCR, reverse transcription-quantitative polymerase chain reaction; SEV, sevoflurane; RAP, rapamycin.