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. 2019 Jul 31;20(4):3085–3094. doi: 10.3892/mmr.2019.10541

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Rapamycin activates sevoflurane-induced autophagy in aged rats. (A) Western blot assays were performed to determine the protein expression levels of LC3II/I, Beclin1 and p62 proteins. (B) An MWM experiment was conducted to determine the effects of autophagy inhibitor treatment on learning and memory abilities. *P<0.05 vs. the control group; ^#P<0.05 vs. the SEV group; ^$P<0.05 vs. the RAP group. MWM, Morris water maze; SEV, sevoflurane; RAP, rapamycin; 3MA, 3-methyladenine.