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. 2019 Aug 21;20(4):3811–3819. doi: 10.3892/mmr.2019.10598

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Expression of E-cadherin and vimentin is regulated by COX-2. MG-63 cells were infected with control or COX-2-overexpressing lentivirus, and treated with or without the COX-2 inhibitor NS398 or the PI3K inhibitor LY294002. (A) The expression of E-cadherin (green) in each group was determined using immunofluorescence. (B) Quantification of E-cadherin expression. (C) The expression of vimentin in each group. (D) Quantification of vimentin expression. Magnification, ×400. ^#P<0.05, ^##P<0.01 vs. plvx-DsRed; *P<0.05, **P<0.01 vs. plvx-COX2-DsRed. COX-2, cyclooxygenase-2; plvx-DsRed, empty vector; plvx-COX2-DsRed, vector overexpressing COX-2.