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. 2019 Aug 6;20(4):3276–3284. doi: 10.3892/mmr.2019.10555

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — RNAi-SLC20A1 suppresses cell proliferation, GH secretion and migration of GH3 cells. (A) Effect on cell viability, as shown by MTS assay. (B) ELISA revealed that RNAi-SLC20A1 could reduce GH secretion. (C) The effect on invasion, as shown by the transwell experiment. Magnification, ×200. (D) The mRNA level of genes associated with migration and invasion upon RNAi-SLC20A1 in GH3 cells. n=3. *P<0.05, **P<0.01 vs. respective control. RNAi, RNA interference; SLC20A1, solute carrier family 20 member 1; GH, growth hormone; sh, short hairpin; E-CAD, E-cadherin; N-CAD, N-cadherin; MMP, matrix metalloproteinase; VEGF, vascular endothelial growth factor.