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. 2019 Aug 26;20(4):3519–3526. doi: 10.3892/mmr.2019.10616

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — miR-608 positively regulates cisplatin sensitivity in non-small cell lung cancer cells. (A) Transfection of miR-608 mimic increased miR-608 expression in A549 cells. (B) Overexpression of miR-608 did not significantly affect viability of A549 cells. (C) Cisplatin treatment decreased viability of A549 cells in a dose dependent manner (5, 10, 15 and 20 µM). (D) Transfection of miR-608 inhibitor decreased miR-608 expression in A549 cells. (E) miR-608 inhibition did not significantly affect viability of A549 cells. (F) Cisplatin treatment decreased viability of A549 cells in a dose dependent manner (5, 10, 15 and 20 µM). ***P<0.001 vs. miR-NC mimic; ^###P<0.001 vs. miR-NC inhibitor. miR, microRNA; NC, negative control.