Table I.
Association between EGFR expression and various clinicopathological features.
| Expression of EGFR | ||||
|---|---|---|---|---|
| Clinicopathological features | n | Positive, n (%) | Negative, n (%) | P-value |
| Sex | 0.798 | |||
| Male | 32 | 11 (34.4) | 21 (65.6) | |
| Female | 10 | 3 (30.0) | 7 (70.0) | |
| Age, years | 0.172 | |||
| ≤50 | 15 | 7 (46.7) | 8 (53.3) | |
| >50 | 27 | 7 (25.9) | 20 (74.1) | |
| Histology differentiation | 0.127 | |||
| High | 8 | 5 (62.5) | 3 (37.5) | |
| Moderate | 19 | 7 (36.8) | 12 (63.2) | |
| Low | 15 | 2 (20.0) | 13 (80.0) | |
| Liver cirrhosis | 0.35 | |||
| Yes | 36 | 11 (30.6) | 25 (69.4) | |
| No | 6 | 3 (50.0) | 3 (50.0) | |
| α-fetoprotein | 0.469 | |||
| ≤400 | 30 | 11 (36.7) | 19 (63.3) | |
| >400 | 12 | 3 (25.0) | 9 (75.0) | |
| Tumor diameter, cm | 0.116 | |||
| ≤5 | 26 | 11 (42.3) | 15 (57.7) | |
| >5 | 16 | 3 (18.8) | 13 (81.3) | |
| TNM stage | 0.075 | |||
| I/II | 25 | 11 (44.0) | 14 (56.0) | |
| III/IV | 17 | 3 (17.6) | 14 (82.4) | |
| Intravascular tumor thrombus | 0.028a | |||
| Yes | 19 | 3 (15.8) | 16 (84.2) | |
| No | 23 | 11 (47.8) | 12 (52.2) | |
| Portal vein tumor thrombus | 0.736 | |||
| Yes | 5 | 2 (40.0) | 3 (60.0) | |
| No | 37 | 12 (32.4) | 25 (67.6) | |
| Involving the liver capsule | 0.005a | |||
| Yes | 32 | 7 (21.9) | 25 (78.1) | |
| No | 10 | 7 (70.0) | 3 (30.0) | |
a
P<0.05. EGFR, epidermal growth factor receptor; TNM, tumor, node and metastasis.