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. 2019 Aug 6;20(4):3149–3159. doi: 10.3892/mmr.2019.10563

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 7. — miR-671-3p promotes NSCLC cell proliferation, migration and invasion, and suppresses apoptosis by downregulating FOXP2 in vitro. A549 and H1975 cell lines transfected with NC or pcDNA3.1-FOXP2 or pcDNA3.1-FOXP2 and miR-671-3p mimics. (A) Scratch migration assay, scale bar 100 μm. (B) Transwell invasion assay (×100 magnification). (C) Western blotting for detection of MMP-2 and MMP-9 protein levels. All data are presented as the mean ± standard deviation, and each experiment was performed in triplicate. *P<0.05 vs. NC group; ^#P<0.05 vs. pcDNA3.1-FOXP2 group. miR, microRNA; FOXP2, forkhead box P2; NSCLC, non-small-cell lung cancer; NC, negative control; MMP, matrix metalloproteinase.