Table III.
Cox regression analyses for the prognostic value of clinical variables.
| Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
| Variables | HR (95% CI) | P-value | HR (95% CI) | P-value |
| Age (≤45/>45) | 1.014 (0.996–1.032) | 0.138 | – | – |
| Pathologic M (M0/M1) | 4.101 (1.356–12.41) | 0.0677 | – | – |
| Pathologic N (N0/N1) | 2.923 (1.440–5.932) | 1.86×10−3 | 1.535 (0.711–3.315) | 2.76×10−1 |
| Pathologic T (T1/T2/T3/T4) | 1.986 (1.473–2.678) | 2.69×10−6 | 1.900 (0.986–3.662) | 5.51×10−2 |
| Pathologic stage (I/II/III/IV) | 1.594 (1.277–1.989) | 2.20×10−5 | 2.386 (1.097–5.192) | 2.84×10−2 |
| Pathologic grade (1/2/3/4) | 0.943 (0.612–1.452) | 7.89×10−1 | – | – |
| Smoking (reformed/current/never) | 0.984 (0.719–1.346) | 9.18×10−1 | – | – |
| New tumor (yes/no) | 5.637 (3.446–9.22) | 9.22×10−15 | 7.33 (1.833–12.235) | 3.22×10−9 |
| Targeted molecular therapy (yes/no) | 0.953 (0.547–1.659) | 8.64×10−1 | – | – |
| Risk status (high/low) | 3.736 (2.177–6.411) | 3.22×10−7 | 1.359 (1.702–8.905) | 1.28×10−3 |
HR, hazard ratio; CI, confidence interval.