Skip to main content
. 2019 Aug 14;18(4):3053–3061. doi: 10.3892/etm.2019.7887

Figure 4.

Figure 4.

Effects of ASI on the TGF-β1/Smad/miR-192 signaling pathway in rat models of diabetic neuropathy. (A) Reverse transcription-quantitative PCR analysis of relative miR-192, TGF-β1, Smad3, col1, α-SMA and Smad7 expression levels in the sham, model and model + ASI groups. (B) Western blot and (C) subsequent quantification and analysis of TGF-β1, Smad3, col1, α-SMA and Smad7 protein levels in the sham, model and model + ASI groups. Data are presented as the mean ± standard deviation (n=6). *P<0.05 vs. sham group; #P<0.05 vs. model group. ASI, astragaloside IV; TGF-β1, transforming growth factor-β1; miR, microRNA; col1, collagen type 1; α-SMA, α-smooth muscle actin.