Table VIII.

Changes of IL-6 and IL-10 levels.

Variable	Low-dose group (n=44)	Middle-dose group (n=42)	High-dose group (n=39)	F value	P-value
IL-6 (pg/ml)
Before treatment	482.4±36.5	483.8±37.2	486.7±38.8	0.140	0.870
After treatment	308.7±28.3	226.3±21.8b	118.7±21.7a,b	635.062	<0.001
t value	26.807	41.076	55.450
P-value	<0.001	<0.001	<0.001
IL-10 (µg/ml)
Before treatment	124.6±11.8	126.5±10.9	123.4±14.5	0.644	0.527
After treatment	142.5±21.2	168.9±20.8b	211.6±24.5a,b	101.621	<0.001
t value	4.262	9.987	17.961
P-value	<0.001	<0.001	<0.001

^aP<0.05 compared with the middle-dose group

^bP<0.05 compared with low-dose group.