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. 2019 Aug 1;6(18):1900610. doi: 10.1002/advs.201900610

Figure 5.

Figure 5

Therapeutic evaluations of AON in mice with DSS‐induced chronic colitis. A) The scheme of treatment procedures. Changes in the B) mouse body weight and C) DAI during 30 days of treatment. *p < 0.05, **p < 0.01, ***p < 0.001, and ns (no significance) versus the colitis group. Representative photos of D) colons, E) the colon length, and F) H&E‐stained histological sections of colonic tissues. Scale bars, 5 mm. The levels of representative inflammatory cytokines including G) TNF‐α, H) IFN‐γ, and I) IL‐1β in colonic tissues. The levels of oxidative mediators including J) MDA, K) H2O2, and L) MPO. For data in (E) and (G)–(L), *p < 0.05, **p < 0.01, ***p < 0.001; ns, no significance. All data are presented as mean ± SE (n = 6).