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. 2018 Nov 1;19(1):100. doi: 10.1186/s10194-018-0937-0

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — MTDH mRNA expression is affected by rs1835740. MTDH mRNA expression levels were normalized to the reference gene PDHB and to a reference sample consisting of pooled cDNA from all individuals. Horizontal bars represent group means, SEM in error bars, groups were compared using an unpaired, two-tailed t-test. a) mRNA levels are compared between individuals with two major alleles (CC) and individuals carrying one or more T alleles (CT + TT) at rs1835740 regardless of headache diagnosis, p = 0.0318. b) mRNA levels were compared between healthy control subjects and individuals with cluster headache, p = 0.195