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. 2018 Oct 4;10:48. doi: 10.1186/s13321-018-0302-y

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Factorial ANOVA with the similarity measures as the factor. Average values are marked with blue dots and the blue lines below and above the dots denote 95% confidence intervals. Normalized SRD values [%] are plotted against the similarity measures. The red dashed lines are arbitrary thresholds defined to select the best few metrics, and to identify the region with the less consistent similarity measures