FIG 2.

Comparison of DppA from H. pylori with other type II/cluster C SBPs. HpDppA, DppA from H. pylori SS1; YpDppA, periplasmic dipeptide transport protein from Y. pestis; EcDppA, dipeptide-binding protein from E. coli; PsDppA, dipeptide-binding protein from Pseudoalteromonas sp. SM9913; HpGbpA, glutathione-binding protein A from H. parasuis SH0165; BsAppA, oligopeptide-binding protein from B. subtilis. (A) A cartoon representation of the structures of different peptide-binding proteins, indicating that the overall fold of HpDppA is largely conserved in other bacterial peptide-binding proteins. (B) Superimpositions of the ribbon diagram of HpDppA (blue) with those of YpDppA (cyan), EcDppA (yellow), PsDppA (pink), HpGbpA (orange), and BsAppA (green).