FIG 1.

Genetic model for the T6SS in FQ-A001. (A) Cartoon of the T6SS in V. fischeri based on the homologous system in V. cholerae. The contracted state of the needle is shown. OM, outer membrane; IM, inner membrane. (B) Main and auxiliary gene clusters of the T6SS in the FQ-A001 genome. Several genes are colored in accordance with the model shown in panel A. Genes adjoining one another in ES114 are shown in black. Similarity was determined by progressiveMauve alignment; regions without color (red for chromosome [Ch] I; blue for Ch II) represent loci at which there is not syntenic DNA in the other strain. The hcp ORF on FQ-A001 chromosome II (VFFQA001_15605) is syntenic with MJ11 VFMJ11_A0831; the hcp1 ORF on FQ-A001 chromosome I (VFFQA001_07840) is syntenic with MJ11 VFMJ11_1495.