Figure 2.

Metabolic requirements underlying the transition between the different stem cell states. The metabolic shifts underlying the transition between the different stem cell states are depicted above, as blue arrows point out the directionality of the metabolic shift, which was reported necessary for achieving the new stem cell state. The black arrow marks the decline in stem cell potency. Note that whereas the requirements for OXPHOS and glycolysis are diverse, the decrease in FAO levels is shared between the different stem cells.