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. 2019 Aug 23;8(17):e011468. doi: 10.1161/JAHA.118.011468

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© 2019 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Association between NT‐proBNP (N‐terminal pro‐B‐type or brain natriuretic peptide)/estimated mature BNP (emBNP) ratios and estimated glomerular filtration rate (eGFR) in patients with acute decompensated heart failure. A, Association between the log emBNP levels and log eGFR. B, Association between the log NT‐proBNP levels and log eGFR. C, Association between the log NT‐proBNP/emBNP ratio and log eGFR. D, Association between the log NT‐proBNP/emBNP ratio and log eGFR in patients with above‐median NT‐proBNP (≥525.4 pmol/L) (red plot) or below‐median NT‐proBNP (<525.4 pmol/L) (blue plot). The interaction term between NT‐proBNP and NT‐proBNP/emBNP ratio was significant (P=0.010).