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. Author manuscript; available in PMC: 2020 Sep 12.
Published in final edited form as: J Med Chem. 2019 Aug 16;62(17):8249–8273. doi: 10.1021/acs.jmedchem.9b01004

Table 13:

FICI values of 5.8a combined with clinical drugs against 7 fungal strains

Fungal strain 5.8a/Flu 5.8a/Vori 5.8a/Itra 5.8a/Caspo 5.8a/AB
C. neoformans 0.237 0.247 0.247 ND 0.247
C. albicans 0.252 0.077 0.091 1.00 ND
Ck Flu R 0.501 1.030 1.240 1.004 ND
Ck6258 0.250 0.560 0.530 1.001 ND
C. auris 0.500 0.500 1.12 0.500 ND
C. parapsilosis 0.258 1.500 1.250 0.501 ND
A. fumigatus 2 1.031 1.008 ND ND

For abbreviation of drug names, see the captions in Table 9.