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. 2019 Sep 18;13:3307–3319. doi: 10.2147/DDDT.S211443

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© 2019 Yang et al.

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Accumulative skin penetration curves of RVC (A) and DMDT (B) from NLCs and solution during 72 hrs of study using Franz diffusion cells with the skin of rats. (Data represent the mean±SD, n=6).

Abbreviations: RVC, ropivacaine; DMDT, dexmedetomidine; TPGS, tocopheryl polyethylene glycol 1000 succinate; NLCs, nanostructured lipid carriers.