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. 2019 Jan 25;33(7):1687–1699. doi: 10.1038/s41375-019-0380-5

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Genetic differences between EBV-negative and -positive DLBCLs. a Frequency and type of somatic alterations identified by targeted-capture sequencing for lymphoma-associated genes in 48 EBV-negative and 27 EBV-positive DLBCL cases. Type of alterations is indicated by color. BCR, B-cell receptor; GCB, germinal center B-cell. *P < 0.05, **P < 0.01, Fisher’s exact test. b Distribution of somatic mutations encoded in MYD88 (NM_002468), CD79B (NM_000626), TET2 (NM_001127208), and FAS (NM_000043) detected in 48 EBV-negative and 27 EBV-positive DLBCL cases. The protein domains were obtained from the NCBI Gene database (https://www.ncbi.nlm.nih.gov/gene/) and the UniProt database (https://www.uniprot.org/)