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. 2018 Nov 26;38(13):2305–2319. doi: 10.1038/s41388-018-0577-5

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Enforced miR-508-3p expression reversed the mesenchymal identify of the mesenchymal subtype ovarian cancer. a Inverse phase microscopy (upper panel) and E-cadherin and vimentin staining (lower panels) of COV504 cells transfected with miR-508-3p mimic or control. Cell nuclei were stained with DAPI. b mRNA levels of key EMT genes in COV504 cells from the same transfection and treated the same way as described above. c Transwell chamber assay of the COV504 cells from the same transfection as described previously. d Wound healing analysis of COV504 cells transfected with miR-508-3p mimic or control for 72 h. In all bar plots, P-values are based on two-tailed Student’s t-tests (*P < 0.05, **P < 0.01)