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. 2019 Sep 16;12:217. doi: 10.3389/fnmol.2019.00217

Figure 4.

Figure 4

HSC-3 xenograft-induced change in orofacial nociceptive behavior was measured in adult nude male (A) and female (B) mice receiving saline (N = 10, open circles) or rG-CSF treatment (2.5 μg/mouse, N = 10, closed circles) 24 h prior to each dolognawmeter measurement, as indicated by the black arrows. Sexes were independently analyzed. Two-way ANOVA, *P < 0.05, **P < 0.01. HSC-3 xenograft-induced weight loss was measured in male (C) and female (D) mice receiving saline (N = 10, open bars) or rG-CSF (2.5 μg/mouse, N = 10, closed bars) each week.