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Recommended analyses for fusion gene rearrangement testing in ALL
| Patient details | Recommended | Optional | |
|---|---|---|---|
| B-ALL | Infants (<1 year old) | KMT2A | ETV6-RUNX1, BCR-ABL1 |
| For paediatric/adolescent ALL (<25 years) | ETV6-RUNX1, BCR-ABL1, then KMT2A and TCF3 | ||
| Adult | BCR-ABL1 then KMT2A and TCF3 | ETV6-RUNX1 | |
| T-ALL | Childhood and adult | TLX3, TLX1, KMT2A, TAL1, LMO2 and ABL1 | |
