Figure 1. Curcumin has a cytotoxicity effect on B16 cells.

B16 cells were treated with or without curcumin (5 µM, 10 µM, 20 µM, 40 µM and 80 µM), and then the cell viability at 48 h (A) and 72 h (B) was determined by MTT assay, respectively. Data were presented as means ± SD. **P < 0.01 vs. ctrl group.