Fig. 1.

Stat6 suppress colitis-associated carcinogenesis a–g. a–g Colitis-associated carcinogenesis (CAC) model performed with WT and Stat6^−/− mice (n = 8/genotype); b, c H&E stained sections of colons and quantification of histological damage after chronic colitis in WT and Stat6^−/− mice (WT n = 5; Stat6^−/− n = 7); d, e Representative H&E stained sections of colonic tumors from WT and Stat6^−/− mice; f, g Histological analysis and quantification of tumor incidence and tumor growth in WT and Stat6^−/− mice at the end of the CAC model (n = 8/genotype). Data are mean ± SEM