Table 3.
Age-adjusted and gender-adjusted OR with 95% CI for associations between invitation for an NHS Health Check and the detection of CVD risk factors, new diagnoses and interventions
| Cohort 1 vs | Cohort 2 vs | Cohort 3 vs | Cohort 4 vs | |||||
| Cohort 5 All |
Cohort 5 DNA |
Cohort 5 All |
Cohort 5 DNA |
Cohort 5 All |
Cohort 5 DNA |
Cohort 5 All |
Cohort 5 DNA |
|
| Detection (%) | ||||||||
| CVD risk >10% | 1.20 (1.15 to 1.25) | 1.71 (1.64 to 1.80) | 1.93 (1.82 to 2.04) | 2.66 (2.50 to 2.83) | 3.28 (3.08 to 3.50) | 3.98 (3.71 to 4.27) | 8.01 (7.34 to 8.73) | 11.17 (10.13 to 12.33) |
| CVD risk >20% | 1.07 (0.99 to 1.15) | 1.49 (1.37 to 1.63) | 1.44 (1.29 to 1.61) | 1.90 (1.69 to 2.15) | 2.83 (2.48 to 3.23) | 3.12 (2.72 to 3.58) | 5.86 (4.83 to 7.10) | 7.18 (5.82 to 8.85) |
| SBP >140 or DBP >90 mm Hg | 1.04 (1.01 to 1.07) | 1.06 (1.03 to 1.09) | 1.08 (1.05 to 1.12) | 1.10 (1.06 to 1.14) | 1.23 (1.19 to 1.27) | 1.26 (1.21 to 1.30) | 1.64 (1.57 to 1.70) | 1.69 (1.62 to 1.76) |
| Current smoker | 1.03 (1.01 to 1.06) | 1.03 (1.01 to 1.06) | 1.05 (1.02 to 1.09) | 1.05 (1.02 to 1.09) | 1.05 (1.02 to 1.08) | 1.05 (1.03 to 1.08) | 1.22 (1.18 to 1.26) | 1.23 (1.19 to 1.27) |
| BMI >30 kg/m2 | 1.09 (1.06 to 1.12) | 1.14 (1.11 to 1.18) | 1.26 (1.21 to 1.31) | 1.31 (1.26 to 1.36) | 1.46 (1.41 to 1.51) | 1.52 (1.47 to 1.58) | 2.05 (1.96 to 2.14) | 2.18 (2.09 to 2.28) |
| TC >5.5 mmol/L | 1.19 (1.16 to 1.23) | 1.33 (1.29 to 1.37) | 1.67 (1.61 to 1.72) | 1.83 (1.77 to 1.90) | 2.10 (2.03 to 2.17) | 2.27 (2.19 to 2.34) | 3.72 (3.57 to 3.89) | 4.20 (4.02 to 4.39) |
| TC >7.5 mmol/L | 1.12 (1.02 to 1.22) | 1.19 (1.08 to 1.30) | 1.42 (1.26 to 1.59) | 1.52 (1.35 to 1.71) | 1.66 (1.47 to 1.87) | 1.76 (1.56 to 1.99) | 2.89 (2.46 to 3.38) | 3.15 (2.67 to 3.72) |
| Diagnoses (%) | ||||||||
| HTN | 1.04 (0.99 to 1.09) | 1.03 (0.98 to 1.09) | 1.06 (0.98 to 1.14) | 1.04 (0.97 to 1.12) | 1.10 (1.02 to 1.19) | 1.10 (1.02 to 1.19) | 1.33 (1.20 to 1.47) | 1.34 (1.20 to 1.48) |
| AF | 1.14 (0.98 to 1.32) | 1.11 (0.95 to 1.30) | 0.91 (0.72 to 1.14) | 0.89 (0.71 to 1.13) | 1.33 (1.06 to 1.67) | 1.31 (1.05 to 1.65) | 1.00 (0.72 to 1.39) | 1.01 (0.72 to 1.40) |
| CKD | 1.01 (0.84 to 1.22) | 0.98 (0.81 to 1.19) | 1.22 (0.93 to 1.61) | 1.18 (0.90 to 1.57) | 1.08 (0.77 to 1.51) | 1.06 (0.76 to 1.49) | 0.69 (0.36 to 1.32) | 0.68 (0.36 to 1.30) |
| Diabetes | 0.99 (0.91 to 1.08) | 0.97 (0.88 to 1.06) | 0.95 (0.84 to 1.09) | 0.94 (0.82 to 1.07) | 1.12 (0.99 to 1.28) | 1.12 (0.98 to 1.27) | 1.34 (1.12 to 1.61) | 1.36 (1.13 to 1.64) |
| Interventions (%) | ||||||||
| Statin | 1.06 (1.01 to 1.11) | 1.12 (1.06 to 1.18) | 1.17 (1.09 to 1.25) | 1.21 (1.13 to 1.30) | 1.26 (1.16 to 1.35) | 1.27 (1.18 to 1.37) | 1.54 (1.39 to 1.71) | 1.58 (1.42 to 1.76) |
| Antihypertensive | 0.99 (0.95 to 1.03) | 0.99 (0.95 to 1.03) | 1.04 (0.99 to 1.10) | 1.04 (0.98 to 1.09) | 1.04 (0.98 to 1.10) | 1.04 (0.98 to 1.10) | 1.15 (1.06 to 1.24) | 1.15 (1.07 to 1.24) |
| Antiglycaemics | 0.93 (0.85 to 1.02) | 0.92 (0.83 to 1.01) | 0.90 (0.79 to 1.04) | 0.90 (0.78 to 1.03) | 1.04 (0.91 to 1.20) | 1.03 (0.90 to 1.19) | 1.18 (0.97 to 1.44) | 1.19 (0.97 to 1.45) |
| Nicotine | 1.00 (0.91 to 1.10) | 1.01 (0.92 to 1.11) | 1.05 (0.91 to 1.22) | 1.07 (0.92 to 1.24) | 1.04 (0.88 to 1.22) | 1.08 (0.91 to 1.28) | 0.92 (0.71 to 1.20) | 0.96 (0.73 to 1.25) |
| Stop smoking advice | 1.08 (1.04 to 1.12) | 1.12 (1.08 to 1.16) | 1.19 (1.13 to 1.26) | 1.23 (1.17 to 1.30) | 1.28 (1.20 to 1.35) | 1.32 (1.25 to 1.40) | 1.65 (1.51 to 1.79) | 1.74 (1.60 to 1.90) |
| Weight advice/referral | 1.50 (1.45 to 1.55) | 2.14 (2.07 to 2.22) | 2.84 (2.73 to 2.95) | 3.98 (3.81 to 4.16) | 4.21 (4.04 to 4.40) | 5.69 (5.42 to 5.98) | 8.36 (7.89 to 8.86) | 14.33 (13.31 to 15.43) |
| Antiobesity | 1.06 (0.88 to 1.26) | 1.06 (0.88 to 1.27) | 1.11 (0.85 to 1.44) | 1.11 (0.85 to 1.44) | 1.09 (0.83 to 1.44) | 1.08 (0.82 to 1.42) | 1.00 (0.68 to 1.48) | 1.00 (0.68 to 1.49) |
| CVD >10% and statin | 1.12 (1.03 to 1.21) | 1.35 (1.24 to 1.48) | 1.27 (1.12 to 1.43) | 1.49 (1.31 to 1.70) | 1.78 (1.54 to 2.07) | 1.90 (1.63 to 2.21) | 2.90 (2.36 to 3.57) | 3.27 (2.63 to 4.06) |
| CVD >20% and statin | 1.03 (0.92 to 1.15) | 1.25 (1.11 to 1.42) | 1.07 (0.90 to 1.28) | 1.28 (1.06 to 1.54) | 1.58 (1.29 to 1.94) | 1.67 (1.36 to 2.06) | 2.60 (1.92 to 3.52) | 2.95 (2.15 to 4.04) |
| HTN and antihypertensive | 1.04 (0.98 to 1.10) | 1.04 (0.98 to 1.10) | 1.06 (0.97 to 1.15) | 1.05 (0.96 to 1.14) | 1.11 (1.02 to 1.21) | 1.11 (1.02 to 1.21) | 1.33 (1.18 to 1.50) | 1.33 (1.18 to 1.50) |
Results are shown for the comparisons of cohorts 1–4 against all of cohort 5 and against patients in cohort 5 who we confirmed did not attend (DNA) an HC incidentally.
AF, atrial fibrillation; BMI, body mass index; CD, cardiovascular disease; CKD, chronic kidney disease; DBP, diastolic blood pressure; HC, Health Check; HTN, hypertension; NHS, National Health Service; SBP, systolic blood pressure; TC, total cholesterol.