Table 1.
Results from unadjusted analyses of clinical and pathological variables (n=716)
| Variable | Frequency | Event number | Median survival-time (year) | HR | P value |
| Gender | 0.40 | ||||
| Female | 163 | 86 | 4.94 | 1.00 | |
| Male | 552 | 314 | 4.59 | 1.10 | |
| Missing | 1 | – | – | – | |
| Borrmann’s type | 0.030* | ||||
| Type I | 29 | 16 | 4.40 | 1.00 | |
| Type II | 514 | 288 | 4.63 | 1.06 | |
| Type III | 57 | 31 | 5.06 | 1.02 | |
| Type IV | 76 | 49 | 2.04 | 1.49 | |
| Type V | 32 | 11 | – | 0.51 | |
| Missing | 8 | – | – | – | |
| Surgical margin | 0.020* | ||||
| Negative | 648 | 353 | 4.94 | 1.00 | |
| Positive | 46 | 34 | 1.55 | 1.71 | |
| Missing | 22 | – | – | – | |
| Lauren’s classification | 0.39 | ||||
| Intestinal type | 214 | 116 | 5.67 | 1.00 | |
| Diffuse type | 468 | 267 | 4.30 | 1.19 | |
| Others | 32 | 16 | 8.95 | 1.03 | |
| Missing | 2 | – | – | – | |
| M stage | <0.0001 * | ||||
| 0 | 684 | 373 | 5.06 | 1.00 | |
| 1 | 28 | 25 | 1.34 | 2.79 | |
| Missing | 4 | – | – | – | |
| N stage | <0.0001* | ||||
| 0 | 257 | 101 | 8.98 | 1.00 | |
| 1 | 169 | 90 | 5.17 | 1.74 | |
| 2 | 169 | 114 | 2.36 | 2.00 | |
| 3 | 117 | 94 | 1.56 | 3.95 | |
| Missing | 4 | – | – | – | |
| T stage | <0.0001* | ||||
| 1 | 63 | 16 | 12.29 | 1.00 | |
| 2 | 73 | 25 | 10.02 | 1.52 | |
| 3 | 533 | 336 | 3.19 | 4.04 | |
| 4 | 33 | 20 | 3.93 | 3.77 | |
| Tis | 11 | 2 | 8.95 | 0.79 | |
| Missing | 3 | – | – | – | |
| Lymph node metastasis rate group | <0.0001* | ||||
| 0 | 257 | 101 | 8.98 | 1.00 | |
| ≤0.35 | 200 | 101 | 5.64 | 1.53 | |
| 0.35–0.74 | 159 | 109 | 2.11 | 2.86 | |
| ≥0.74 | 95 | 81 | 1.50 | 4.25 | |
| Missing | 5 | – | – | – | |
| Surgical type I group | 0.13 | ||||
| All stomach | 579 | 337 | 4.27 | 1.00 | |
| Proximal | 28 | 12 | 6.74 | 0.78 | |
| Distal | 101 | 48 | 8.69 | 0.59 | |
| Missing | 7 | – | – | – | |
| Surgical type II group | <0.0001* | ||||
| Radical | 672 | 363 | 5.25 | 1.00 | |
| Palliative | 42 | 36 | 1.13 | 3.19 | |
| Missing | 2 | – | – | – | |
| Lymphovascular invasion | 0.56 | ||||
| No | 611 | 344 | 4.74 | 1.00 | |
| Yes | 98 | 55 | 4.61 | 1.09 | |
| Missing | 7 | – | – | – | |
| Clinical stage | <0.0001* | ||||
| 0 | 11 | 2 | 8.95 | 1.00 | |
| 1 | 109 | 30 | 12.29 | 1.41 | |
| 2 | 296 | 148 | 5.84 | 3.36 | |
| 3 | 269 | 194 | 2.05 | 7.12 | |
| 4 | 28 | 25 | 1.34 | 11.53 | |
| Missing | 3 | – | – | – | |
| No of cancer nodules group | <0.0001* | ||||
| 0 | 637 | 347 | 5.17 | 1.00 | |
| 1–2 | 55 | 36 | 1.92 | 1.63 | |
| ≥3 | 15 | 13 | 1.38 | 2.86 | |
| Missing | 9 | – | – | – | |
| Tumour size group | <0.0001* | ||||
| ≤4 cm | 299 | 131 | 8.69 | 1.00 | |
| 4–8 cm | 275 | 170 | 3.16 | 1.84 | |
| ≥8 cm | 128 | 95 | 1.90 | 2.54 | |
| Missing | 14 | – | – | – | |
| Invasion depth group | <0.0001* | ||||
| Mucosa | 25 | 4 | – | 1.00 | |
| Submucosa | 40 | 12 | 12.29 | 1.79 | |
| Muscular | 83 | 29 | 10.02 | 2.48 | |
| All layer | 565 | 354 | 3.21 | 6.24 | |
| Missing | 3 | – | – | – | |
| Positive lymph nodes number group | <0.0001* | ||||
| 0 | 257 | 101 | 8.98 | 1.00 | |
| 1–6 | 338 | 204 | 3.58 | 2.06 | |
| 7–15 | 99 | 81 | 1.50 | 4.12 | |
| ≥16 | 18 | 13 | 1.90 | 3.04 | |
| Missing | 4 | – | – | – | |
| Tumour location | 0.0067* | ||||
| Proximal | 399 | 217 | 4.88 | 1.00 | |
| Body | 164 | 96 | 4.61 | 1.07 | |
| Distal | 99 | 48 | 6.14 | 0.91 | |
| More than two sites | 52 | 38 | 1.60 | 1.83 | |
| Missing | 3 | – | – | – | |
| No of retrieved lymph nodes group | 0.10 | ||||
| 0 | 6 | 2 | – | 1.00 | |
| 1–6 | 196 | 103 | 6.10 | 1.77 | |
| 7–15 | 391 | 221 | 4.27 | 2.13 | |
| ≥16 | 116 | 72 | 3.17 | 2.48 | |
| Missing | 7 | – | – | – | |
| Age (missing=1) | 715 | 1.01 | 0.144 | ||
| Age square (missing=1) | 715 | 1.00 | 0.056 | ||
| Positive lymph nodes number (missing=4) |
712 | 1.08 | <0.0001* | ||
| No of retrieved lymph nodes (missing=7) | 709 | 1.02 | 0.014* | ||
| Lymph node metastasis rate (missing=5) |
711 | 1.04 | 0.232 | ||
| No of cancer nodules (missing=9) | 707 | 1.18 | <0.0001* |
*p-value<0.05.