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. 2019 Sep 20;9(9):e030639. doi: 10.1136/bmjopen-2019-030639

Table 2.

Results from adjusted analysis of prognostic variables

Variables Estimated coefficient Estimated
SE
Estimated
HR
95% CI of HR P value
Age −0.119 0.038 0.888 0.825 to 0.956 0.0016*
Age square 0.001 0.0003 1.001 1.000 to 1.002 0.0005*
No of cancer nodules 0.103 0.040 1.108 1.024 to 1.199 0.0106*
Lymph node metastasis rate group <0.0001*
 0 (reference) 1.000
 ≤0.35 −0.033 0.152 1.033 0.768 to 1.390
 0.35–0.74 0.577 0.153 1.780 1.320 to 2.401
 ≥0.74 0.825 0.169 2.491 1.774 to 3.497
Invasion depth group 0.0041*
 Submucosa 1.000 (– to –)
 Mucosa −0.880 0.776 0.415 0.091 to 1.898
 Muscular 0.256 0.370 1.291 0.625 to 2.669
 All layer 0.740 0.334 2.095 1.089 to 4.032
Surgical type
II group
<0.0001*
 Radical
 Palliative 1.757 0.364
Tumour size 0.0010*
 ≤4 cm (reference)
  4–8 cm 0.240 0.132
  ≥8 cm 0.566 0.152
Surgical type
II group* tumour size
0.0003*
 Palliative versus radical ≤4 cm (reference)
 Palliative 4–8 cm −1.026 0.453
 Palliative ≥8 cm −2.097 0.517

*p-value<0.05.