Table 2.
Enriched functions for the target genes of the upregulated miRNAs
| Terms | Count | P-Value |
|---|---|---|
| Biological process (BP) | ||
| GO:0000122~negative regulation of transcription from RNA polymerase II promoter | 20 | 3.13E-04 |
| GO:0043966~histone H3 acetylation | 5 | 0.001185 |
| GO:0045732~positive regulation of protein catabolic process | 5 | 0.004059 |
| GO:0045944~positive regulation of transcription from RNA polymerase II promoter | 21 | 0.004878 |
| GO:2,000,637~positive regulation of gene silencing by miRNA | 3 | 0.004965 |
| GO:0046902~regulation of mitochondrial membrane permeability | 3 | 0.004965 |
| GO:0006351~transcription, DNA-templated | 34 | 0.00638 |
| GO:0035278~miRNA mediated inhibition of translation | 3 | 0.007179 |
| GO:0060707~trophoblast giant cell differentiation | 3 | 0.007179 |
| GO:0009791~post-embryonic development | 5 | 0.008128 |
| Cellular component (CC) | ||
| GO:0030133~transport vesicle | 7 | 4.03E-04 |
| GO:0005634~nucleus | 76 | 8.63E-04 |
| GO:0005794~Golgi apparatus | 20 | 0.001193 |
| GO:0030173~integral component of Golgi membrane | 5 | 0.00279 |
| GO:0005741~mitochondrial outer membrane | 7 | 0.004076 |
| GO:0005654~nucleoplasm | 42 | 0.007228 |
| Molecular function (MF) | ||
| GO:0003725~double-stranded RNA binding | 6 | 4.66E-04 |
| GO:0005515~protein binding | 116 | 6.09E-04 |
| GO:0003700~transcription factor activity, sequence-specific DNA binding | 22 | 0.001318 |
| GO:0035197~siRNA binding | 3 | 0.003002 |
| GO:0046872~metal ion binding | 35 | 0.005995 |
| KEGG_PATHWAY | ||
| hsa05206: microRNAs in cancer | 10 | 0.001587 |