Table 3.
List of the Entry Numbers and Hit Percentages (%) of Target-Specific Druglike Datasets
| GPCR | ion | kinase | protease | |||||
|---|---|---|---|---|---|---|---|---|
| SS | no. entries | HP | no. entries | HP | no. entries | HP | no. entries | HP |
| 85 | 25595 | 0.1 | 22000 | 0.1 | 9573 | 0.1 | 40101 | 0.2 |
| 80 | 44673 | 0.2 | 42126 | 0.2 | 17677 | 0.1 | 84264 | 0.4 |
| 75 | 96741 | 0.5 | 94513 | 0.5 | 36471 | 0.2 | 177168 | 0.9 |
| 70 | 231963 | 1.2 | 233155 | 1.2 | 83746 | 0.4 | 376400 | 2.0 |
| 65 | 557328 | 3.0 | 548882 | 2.9 | 197394 | 1.0 | 801259 | 4.2 |
| 60 | 1234291 | 6.5 | 1169750 | 6.2 | 467769 | 2.5 | 1661329 | 8.8 |
| 55 | 2505668 | 13.3 | 2363312 | 12.5 | 1161054 | 6.2 | 3293679 | 17.5 |
| 50 | 4293284 | 22.8 | 4177077 | 22.1 | 2676629 | 14.2 | 5733633 | 30.4 |