. 2019 Sep 23;14(9):e0221615. doi: 10.1371/journal.pone.0221615

Table 5. Changes in fasting lipids.

Parameter	Open-Label Treatment Period			Double-Blind Treatment Period
	Open-Label Treatment Period			DCCR		Placebo		p-value^*
	n	Change from Baseline	p-value	n	Change from Baseline	n	Change from Baseline	p-value^*
Triglycerides	7	-24.2%	0.15	4	-40.3%	6	-31.5%	0.046
Total Cholesterol	8	-6.3%	0.07	3	-8.8%	6	2.7%	0.10
Non-HDL Cholesterol	8	-11.0%	0.03	4	-4.3%	6	5.3%	0.52
LDL Cholesterol	8	-12.5%	0.03	4	-7.2%	6	-8.1%	0.38

*Based on ANCOVA