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. 2019 Sep 23;14(9):e0222787. doi: 10.1371/journal.pone.0222787

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© 2019 Aso et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 7 — Removal of the lag structure or deperfusioning resulted in the greatest reduction of the signal variance under all 3 tasks (left panels). Nevertheless, the spurious negative task responses were attenuated in comparison to the removal of global fluctuation (middle and right panels). Error bars indicate the standard deviation. The vertical broken line in the histogram indicates the statistical height threshold of p = 0.05, corrected for multiple comparisons by the family-wise error (FWE) rate. GSR, global signal regression; SPM, SPM12 software.