Table 3. Rate of positive serum PCRs in the various clinical categories, according to Schistosoma species (n = 194 patients).
Diagnosis | Number of positive PCR in serum n/N (%) | Median Ct value for both PCRs | ||
---|---|---|---|---|
SmPCR and/or ShPCR | ShPCR | SmPCR | ||
Schistosomiasis (N = 99) | 72a/99 (72.7) | 22/99 (22.2) | 56/99 (56.6) | 34.1 [32.0; 36.1] |
Proven N = 34 | 32/34 (94.1) | 13/34 (38.2) | 22/34 (64.7) | 32.9 [30.9; 35.1] |
Urogenital N = 13 | 11/13 (84.6) | 11/13 (84.6) | 1b/13 (7.7) | |
Intestinal N = 18 | 18/18 (100.0) | 0/18 (0) | 18/18 (100) | |
Mixed infection N = 2c | 2/2 (100) | 2/2 (100) | 2/2 (100) | |
Undetermined N = 1d | 1/1 (100) | 0/1 (0) | 1/1 (100) | |
Probable active N = 30 | 23e/30 (76.7) | 5/30 (16.7) | 19/30 (63.3) | 34.7 [32.3; 36.6] |
Strictly serological N = 35 | 17f/35 (48.6) | 4/35 (11.4) | 15/35 (42.9) | 35.0 [32.2; 36.2] |
Excluded schistosomiasis N = 95 | 1/95 (1.1) | 0/95 (0) | 1/95 (1.1) | NA |
NA: not applicable
a6/72 patients had simultaneously positive Sm and ShPCR
bOne serum sample simultaneously yielded positive results for both Sm and ShPCR
cTwo patients had a concomitant detection of Sm in stool and Sh in urine
dOne patient had a positive Sm PCR whereas eggs of Sh or S. intercalatum were microscopically detected in the rectal biopsy
e1/30 was positive for Sm and ShPCR
f2/35 were positive for Sm and ShPCR