Fig. 1.

A 33-year-old patient is shown (A) and (B) 6 years later, just before receiving full facial ITR² rejuvenation. In (B), the subtle signs of aging around the eyes, marionette basins, cheeks and pyriform region can be appreciated. At this stage, by replacing the lost volume in an anatomically precise manner that addresses all areas of deep and superficial fat loss, bone loss, skin atrophy, and photodamage, tissue mass is increased, blood supply improved, sustaining and replacing lost tissues and reducing or even reversing some elements of decay, and aging. C, Patient is shown 6 months after ITR². ITR², injectable tissue replacement and regeneration.