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. 2019 Sep 19;12:2987–3015. doi: 10.2147/IDR.S218584

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© 2019 Wu et al.

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NS5B RASs rate with significantly different frequencies among different geographic regions. In each plot, the first bar represents the global prevalence and geographic regions were arranged in descending order according to the frequency of RASs. Sequences were clustered into Asia, Europe, North America, Central America, South America, Former USSR, Oceania, Africa, Caribbean or Middle East. In each plot, only regions with at least 10 sequences were shown. Region definition was according to the Los Alamos HCV Database. “A” in North A, South A and Central A denotes America.